Dr. Thaddeus S. "Rusty" Venture - Stephen Colbert
The Monarch - Adrien Brody
Brock Sampson - Patrick Warburton (No one else could do him justice, just slap a mullet on him!!)
Hank Venture - Jorma Taccone
Dean Venture - Rupert Grint
Dr. Girlfriend - Scarlett Johansson (Lets put that husky voice to good use!)
21 - Kevin Smith
24 - Adam Carolla
Moltov Cocktease - Milla Jovovich
Dr. Orpheus - Christopher Lee
Triana Orpheus - Anne Hathaway
Pete White - Alan Cummings
Master Billy Quizboy - Andy Richter
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